表观遗传学 电子书 下载 txt pdf mobi

《表观遗传学》简介：生命是一个复杂的过程，有很多的例外情况，许多最关键的现象往往不能用已有理论来解释。表观遗传学正是这些例外的基础之上发展成型的。这些非DNA变化但可继承的现象与癌、衰老、动植物发育等热点问题密切相关，爱到广泛关注。《表观遗传学》是表观遗传学领域领军人物的扛鼎之作，是该领域第一本系统性、权威性论著，不仅涉及一线研究的方方面面，还用专门章节讲述了表观遗传学的发展历程。

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书籍介绍

《表观遗传学》简介：生命是一个复杂的过程，有很多的例外情况，许多最关键的现象往往不能用已有理论来解释。表观遗传学正是这些例外的基础之上发展成型的。这些非DNA变化但可继承的现象与癌、衰老、动植物发育等热点问题密切相关，爱到广泛关注。《表观遗传学》是表观遗传学领域领军人物的扛鼎之作，是该领域第一本系统性、权威性论著，不仅涉及一线研究的方方面面，还用专门章节讲述了表观遗传学的发展历程。

• 作者： Woody_Sinbad 发布时间：2017-04-19 00:03:40

  以后哈，拜托做不出实验，没有idea的这些老板们，别拿来外国教材瞎翻译了....你们语文是Google翻译教的么？敢不敢说句人话试试？？

• 作者： 远古巨型茄子 发布时间：2009-09-20 20:04:56

  我的意思是我在书店看见过这本书...

• 作者： Y 发布时间：2022-12-15 20:05:30

  朱冰老师翻译的书居然打这么低，我个人觉得这本书很好，可能是被朱老师人格魅力征服了吧，要配合国科大朱老师的表观遗传学这门课一起食用效果更佳，现在表观遗传领域已经有很多重大的进展了，个人觉得这本书作为表观遗传学入门是必备的，期待老师把新的一版翻译出来，这本还是有点老了（因为懒所以不想读英文原著

• 作者： (。-`ω´-) 发布时间：2016-09-13 20:37:00

  表冠遗传学会流行好一阵子

• 作者： 靖雯雯雯雯靖 发布时间：2022-05-23 13:47:07

  实在是很boring的书

• 目录

  作者：cylala 发布时间：2021-05-24 22:33:50

  Preface

  Acknowledgments

  1 A Brief History of Epigenetics

  Gary Felsenfeld

  2 The Next Generation: Young Scientists Forging Exciting New Discoveries in Epigenetic Research

  The Discovery of Histone Demethylases

  Yujiang Geno Shi and Yu-ichi Tsukada

  Cellular Reprogramming

  Kazutoshi Takahashi

  IncRNAs: Linking RNA to Chromatin

  John L. Rinn

  Enhancer RNAs: A Class of Long Noncoding RNAs Synthesized at Enhancers

  Tae-Kyung Kim, Martin Hemberg, and Jesse M. Gray

  Expanding the Epigenetic Landscape: Novel Modifications of Cytosine in Genomic DNA

  Skirmantas Kriaucionis and Mamta Tahiliani

  Plant Mobile Small RNAs

  Patrice Dunoyer, Charles Melnyk, Attila Molnar, and R. Keith Slotkin

  CpG Island Chromatin Is Shaped by Recruitment of ZF-CxxC Proteins

  Neil P. Blackledge, John P. Thomson, and Peter J. Skene

  Bromodomain and Extraterminal Domain Inhibitors (BETi) for Cancer Therapy: Chemical Modulation of Chromatin Structure

  Jun Qi

  Pharmacological Inhibition of Bromodomain-Containing Proteins in Inflammation

  Uwe Schaefer

  Histone H3 Mutations in Pediatric Brain Tumors

  Xiaoyang Liu, Troy A. McEachron, Jeremy Schwartzentruber, and Gang Wu

  Chromosome Folding: Driver or Passenger of Epigenetic State?

  Tom Sexton and Eitan Yaffe

  3 Overview and Concepts

  C. David Allis, Marie-Laure Caparros, Thomas Jenuwein, Monika Lachner, and Danny Reinberg

  4 Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition

  Ronen Marmorstein and Ming-Ming Zhou

  5 Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

  Edward Seto and Minoru Yoshida

  6 Structural and Functional Coordination of DNA and Histone Methylation

  Xiaodong Cheng

  7 A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks

  Dinshaw J. Patel

  8 Epigenetics in

  Saccharomyces cerevisiaeMichael Grunstein and Susan M. Gasser

  9 Epigenetic Regulation of Chromatin States in

  Schizosaccharomyces pombeRobin C. Allshire and Karl Ekwall

  10 Neurospora crassa, a Model System for Epigenetics Research

  Rodolfo Aramayo and Eric U. Selker

  11 Epigenetics of Ciliates

  Douglas L. Chalker, Eric Meyer, and Kazufumi Mochizuki

  12 Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in

  DrosophilaSarah C.R. Elgin and Gunter Reuter

  13 Epigenetic Regulation in Plants

  Craig S. Pikaard and Ortrun Mittelsten Scheid

  14 The Use of Mouse Models to Study Epigenetics

  Marnie Blewitt and Emma Whitelaw

  15 DNA Methylation in Mammals

  En Li and Yi Zhang

  16 RNAi and Heterochromatin Assembly

  Robert Martienssen and Danesh Moazed

  17 Transcriptional Silencing by Polycomb-Group Proteins

  Ueli Grossniklaus and Renato Paro

  18 Transcriptional Regulation by Trithorax-Group Proteins

  Robert E. Kingston and John W. Tamkun

  19 Long-Range Chromatin Interactions

  Job Dekker and Tom Misteli

  20 Histone Variants and Epigenetics

  Steven Henikoff and M. Mitchell Smith

  21 Nucleosome Remodeling and Epigenetics

  Peter B. Becker and Jerry L. Workman

  22 Maintenance of Epigenetic Information

  Geneviève Almouzni and Howard Cedar

  23 Regulation of the X Chromosomes in

  Caenorhabditis elegansSusan Strome, William G. Kelly, Sevinc Ercan, and Jason D. Lieb

  24 Dosage Compensation in

  DrosophilaJohn C. Lucchesi and Mitzi I. Kuroda

  25 Dosage Compensation in Mammals

  Neil Brockdorff and Bryan M. Turner

  26 Genomic Imprinting in Mammals

  Denise P. Barlow and Marisa S. Bartolomei

  27 Germline and Pluripotent Stem Cells

  Wolf Reik and M. Azim Surani

  28 Induced Pluripotency and Epigenetic Reprogramming

  Konrad Hochedlinger and Rudolf Jaenisch

  29 Epigenetic Control of Immunity

  Meinrad Busslinger and Alexander Tarakhovsky

  30 Metabolic Signaling to Chromatin

  Shelley L. Berger and Paolo Sassone-Corsi

  31 Epigenetic Regulation in Plant Responses to the Environment

  David C. Baulcombe and Caroline Dean

  32 Histone and DNA Modifications as Regulators of Neuronal Development and Function

  Stavros Lomvardas and Tom Maniatis

  33 Epigenetics and Human Disease

  Huda Y. Zoghbi and Arthur L. Beaudet

  34 Epigenetic Determinants of Cancer

  Stephen B. Baylin and Peter A. Jones

  35 Histone Modifications and Cancer

  James E. Audia and Robert M. Campbell

  36 The Necessity of Chromatin: A View in Perspective

  Vincenzo Pirrotta

  Appendix 1: WWW Resource PagesAppendix 2: Comprehensive Catolog of Currently Documented Histone Modifications

  Yinming Zhao and Benjamin A. Garcia

  Index